William and Catherine left Buckingham Palace by helicopter on Saturday, following their wedding parties.
They celebrated at the palace with 300 friends and family on Friday evening, after a larger lunchtime reception.
Meanwhile, Clarence House has released three official wedding photographs.
The locations of the couple’s UK weekend and their honeymoon – which will be overseas – will not be disclosed in advance.
The couple have asked that their privacy be respected during the coming days, and while on their honeymoon.
The couple emerged hand-in-hand from Buckingham Palace’s garden entrance on Saturday morning.
The couple, who had spent the night at the Queen’s official London home, stopped briefly to chat to two Royal Household footmen before boarding the helicopter.
Prince William will go back to his job as an RAF search and rescue pilot next week. They live on Anglesey, but St James’ Palace said they will not be spending the long weekend there.
‘A little jaded’
The reception at the palace on Friday night, hosted by the Prince of Wales, is believed to have featured Prince Harry’s best man speech and Michael Middleton’s father-of-the-bride address.
The bride wore a white evening gown by Sarah Burton, who created her wedding dress, to the event.
Her sister Pippa changed for the party into a long emerald green sleeveless dress with a jewelled embellishment on the front and a plunging neckline.
Middleton family friend Tony Ainsworth said: “I hear everyone’s talking about Pippa. She looked stunning. She’s the most eligible girl in the country right now.”
The duchess’s family, along with some of their guests, stayed at the exclusive Goring hotel near the palace.
The couple walked in the grounds of Buckingham Palace before flying to an undisclosed location
Mr Ainsworth, from Dorset, said outside the hotel that the wedding had been “an historic occasion”.
“After the concerns of getting to the church on time, it all went smoothly.
“We had a party at the hotel last night that went on well into the evening, so we’re feeling a little jaded this morning.”
He said the bride’s parents had made an appearance after attending the reception at Buckingham Palace.
The official photographs of the wedding were released on Saturday, as the couple departed.
The pictures were taken in Buckingham Palace’s throne room immediately after the bride and groom arrived from their marriage service at Westminster Abbey on Friday.
Three photos have been released, with one showing the couple alone, and a second that includes their bridesmaids and pageboys.
The final image adds the bride and groom’s parents – the Prince of Wales, the Duchess of Cornwall and Michael and Carole Middleton – along with the Queen, the Duke of Edinburgh, Prince Harry, maid of honour Pippa, and the bride’s brother James.
The Middleton family left the Goring, which they had booked out entirely for the wedding preparations, on Saturday.
Mr Middleton told the gathered crowd: “We had a wonderful time.”
An estimated one million well-wishers gathered in London for the wedding.
The service at the abbey was watched by 1,900 guests and ran smoothly, aside from a brief struggle to place the wedding ring on the bride’s finger.